Download our free whitepaper: Benefits of Comprehensive Two-Dimensional Gas Chromatography (GCxGC) for a Routine Laboratory, authored by Michelle Misselwitz, Chemistry Consultant at Chemistry Matters, Inc., for more information on how GCxGC can benefit your laboratory.
QuadJet SD: Flame Ionization Detection meets GCxGC
- Enhanced separating power for complex sample analysis
- Easy-to-use ChromaTOF-based software provides acquisition processing and reporting funtionality within a single package
- Classification software feature simplifies component identification
- Available Cryogen-free modulator eliminates the need for LN2 dewars
Theory of Operation
When performing GC-FID analysis, most laboratories quantify compounds using the area of the FID signal. Real world samples are rarely clean and straightforward. For example, a diesel sample can have thousands of different compounds in a single injection. The more compounds in a sample, the higher the chance of coelution; this coelution will increase the FID signal, thus creating a high bias error in the measurement. With GCxGC performing two separate chromatographic separations in one experiment, the accuracy of the FID measurement is maintained.
Due to the orthogonal nature of the separation mechanism in GCxGC, coeluting compounds are easily pulled apart in a single run. True GCxGC instruments, such as the LECO QuadJet SD, improve upon simply running the same sample through two different columns by incorporating a modulation device. Peaks eluting from the primary column are quantitatively segmented into smaller sections prior to release onto the second column. This segmenting, along with the cryo-focusing of the modulator, can deliver peak widths as narrow as 50 ms to the second column.
There is no better-performing modulator for GCxGC than thermal modulation, and not even other thermal modulators can match up to the ruggedness, reliability, and performance of LECO's GCxGC modulator. With LECO's QuadJet SD, modulation is accomplished via a dual-stage, quad-jet thermal modulator positioned between the two columns. LECO's thermal modulator allows for on-column cryo-focusing within the GCxGC system, providing increased peak detectability and increased separation of coeluting compounds for an order-of-magnitude increase in signal-to-noise.
LECO's Consumable-Free Modulator (which does not utilize Liquid Nitrogen) is an available option, saving time and money without sacrificing performance when modulating moderately volatile compounds.
LECO's QuadJet SD is designed to give you the upper hand in laboratory productivity. Its ease-of-use and industry's best secondary oven for the secondary column allows for improved analytical results. When you take the step to the next dimension in gas chromatography, make sure you're taking the step that will let you see what you've been missing.